Slay the Spire 2 Guides — Characters, Co-op and Enchantments

All 88 cards by rarity and type, with the counts behind Doom, Osty and Summon.

How the Regent stacks Stars and forges the Sovereign Blade into a scaling weapon.

Every Sly card with its cost and effect, plus the discard rule that decides whether the keyword fires.

A flat bonus to your next Attack that survives between turns. All five sources with real values, and why a cheap poke wastes the stack.

70 HP, Ring of the Snake, and the three builds that win long games: the reliable poison stack, the Shiv ceiling, and the Sly discard engine.

Every Slay the Spire 2 event from Overgrowth to the Hive, with the removal and Max HP trades worth taking and the cursed gold to avoid.

A system-by-system table of what carried over and what the sequel rebuilt.

Up to four players, separate decks, one shared route, and how to fix the usual problems.

Every enchantment in one table with its effect, plus how to read the scaling X values.

Every relic with effect, rarity and the pool that gates it.

How to rank all 296 relics by what they do, with priority rules instead of vibes.

An if-then framework for when to grab a card and when to thin your deck, by stage and character.

The habits that stop working in Slay the Spire 2, with the fix for each — built from confirmed mechanics.

The full card database, filterable by character, with every card's text.

Every potion with its rarity and effect.

Every boss, elite and normal enemy with HP, moves and attack pattern.

Every keyword in the game, defined.

No — she is not in early access. Meet the five characters who are, and what to play instead.

The sequel launched at Ascension 10. What changed from the first game and what is still rising.

The skeletal hand Osty, the Soul resource, and the Doom status that drive her kit.

Doom is the Necrobinder’s stacking status. How to build it and cash it in.

All 21 Star cards, the 16 that generate Stars, and the 12 that Forge the Sovereign Blade.

The Silent returned with Sly: cards that auto-play when discarded. What moved from STS1.

The default starter: his 87-card pool built on Strength scaling, self-damage, and Exhaust payoffs.

The last character to unlock: his 88-card pool is orb-centric and the most Skill-heavy in the roster.

The Necrobinder's exhaust pile becomes fuel. How to use it without guessing numbers.

The new combat mechanic where enemies debuff the cards you own, not just your HP. How to spot and route around them.

Act 1 splits into Overgrowth and the Underdocks. How the map branches and what it changes for routing.

The new card type that clogs your deck until you meet its condition. The three in the build and their payoffs.

No matchmaking. Lobbies are Steam-friends only, and how to start a session.

No full crossplay. Co-op is Steam-friends only, and the OS picture.

The five characters with playstyle and card pool size, plus the win chain that gates four of them.

All 8 Ancients, which act each appears in, and how the relic pools and offer rates work.

The Act 1 opener: the Curse pool, the shifting Positive pool, and the boon rates that shape your run.

The Act 2 Ancient: one relic from each of three pools, every relic, and the real offer rates.

The Act 2 Colorless-Energy Ancient: three pools, the deck-conditional relics, and the rates.

The Act 2 fire-and-food Ancient: three pools, the Strike-gated relic, and the offer rates.

The only Ancient in Act 2 and Act 3: returning boss relics plus a character-specific ancient card.

The Act 3 Ancient: three random relics from a ten-relic pool, the conditional relic, and the rates.

The Act 3 weapon Ancient: three weapon relics from a ten-relic pool, the Instinct condition, and the rates.

The Act 3 First Demon: three pools of big-upsides-with-costs, every relic, and the offer rates.

Block before damage, small decks before big ones, and why one Ironclad win opens the whole roster.

The four repeated choices that shape a run: take or skip, upgrade or rest, remove or add, commit or hedge.

Every character’s real build lanes — Ironclad Strength and Exhaust, Silent Poison and Sly, Defect Orbs, Necrobinder Doom and Osty, Regent Stars.

Every rarity tier from Starter through Ancient, plus the character tags that decide which relics you see.

All 199 measurable cards ranked by damage or Block per Energy, with the method and the gaps spelled out.

Every major Slay the Spire 2 update in 2026: Aeonglass replacing Doormaker, the Poison rebuild, Quest Cards, co-op and the RNG rework.

Most crashes are a renderer conflict, not a broken PC. The --rendering-driver opengl3 flag, the Direct3D error decoded, and the order to try the rest.

Nothing unlocks by itself. Epoch rewards wait on the Timeline until you claim them, plus the seven-step chain and how Ancient cards actually arrive.

Plow buffs into Charges, then a Stun that strips its own Strength.

A trio fight where killing the Priest ends it, but the followers keep hitting.

Nine Slippery stacks absorb your first hits. Multi-hit cards burn them fastest.

Sleeps three turns behind Plating. Use the free turns, then survive Soul Siphon.

A strict five-turn cycle with an Intangible window. Time your big attacks.

Builds Steam Eruption all fight, then explodes for everything it stored.

Two claws at once. Focus the Rocket claw first, and do not waste hits on Block.

Every cycle forces a worse Curse into your deck. Speed is the whole answer.

A Sandpit timer kills you outright. Win fast or the clock wins.

Break the Door, burst the stun window, and block the Big Swing before it reforms. Legacy boss — replaced by Aeonglass in 0.107.1.

The current Act 3 Glory boss. A fixed Ebb, Eye Lasers, Increasing Intensity cycle, plus 3 starting Artifact.

The Act 3 finale is a scripted event, not a fight: 9,999 HP, one move called Nothing, and your damage becomes the run score.

Her rotation is fixed. Kill the Amalgam first and spend Artifact on the debuffs.

Three phases that punish Skills, unblocked hits, and multi-hit attacks in turn.

The habits that decide runs: read intent before you block, keep the deck thin, and upgrade at campfires above 50% HP.

All 22 enchantments listed, with effects where confirmed, grouped by what they change.

All 296 relics with rarity and effect, grouped from Starter through Ancient.

All 63 potions with rarity and effect, in one lookup table.

Bosses with HP, difficulty and the key mechanic that decides each fight.

All 577 cards with cost, type and rarity, grouped by which character can play them.

All 199 measurable cards ranked by damage or Block per Energy, with the method and the gaps laid out.