Antewise

How to Beat Soul Fysh in Slay the Spire 2

Updated 16 Oct 2026 Source STS2 Companion boss guide, retrieved 16 October 2026 By
Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.

Soul Fysh is a boss in Slay the Spire 2. Here is what she or he does, the moves to expect, and the order that actually wins.

A rhythm-based boss that cycles between attacks, Beckon status cards, and Intangible windows on a strict 5-turn rotation.

The fight at a glance

ActAct 1b
LocationUnderdocks
DifficultyHard
HP211
Key mechanicBeckon / Intangible Cycle

The rotation

Strict 5-turn cycle: Beckon (turn 1) → Lure (turn 2) → Nibble (turn 3) → Intangible (turn 4) → Vulnerable Bite + Intangible (turn 5), then repeats.

Moves

MoveWhat it does
BeckonPlaces Beckon cards in your draw pile and discard pile. Holding a Beckon at end of turn deals 6 unblockable damage.
LureAttack dealing ~15 damage.
NibbleLight attack dealing ~8 damage and adding another status card.
IntangibleAll damage received is reduced to 1 per hit for the turn.
Vulnerable BiteDeals ~10 damage and applies 3 stacks of Vulnerable while still Intangible.

How to beat Soul Fysh

  • Learn the 5-turn rhythm. Dump all your damage on turns 1-3 when Soul Fysh is vulnerable. On turns 4-5 (Intangible), focus on defense and discarding Beckon cards instead of wasting attacks. Discard effects and small deck size help manage the Beckon cards. Multi-hit attacks are useless during Intangible — save them for the vulnerable window.
  • Never hold a Beckon card at end of turn — it deals 6 unblockable damage
  • Discard effects help dump Beckons without wasting your whole turn
  • Don’t waste big attacks during Intangible turns (4-5) — save them for turns 1-3
  • A smaller, leaner deck draws Beckons more predictably

Where to go next

The boss table lists every boss with HP and key mechanic. The deckbuilding basics page covers building for fights like this one.

Frequently asked questions

How much HP does Soul Fysh have?

211 HP in Slay the Spire 2.

What is Soul Fysh's key mechanic?

Beckon / Intangible Cycle

How do you beat Soul Fysh?

Learn the 5-turn rhythm. Dump all your damage on turns 1-3 when Soul Fysh is vulnerable. On turns 4-5 (Intangible), focus on defense and discarding Beckon cards instead of wasting

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.