Antewise

Slay the Spire 2 Relic Tier List & Evaluation Guide

Updated 17 Oct 2026 Source spire-codex.com STS2 API, retrieved 17 October 2026 By
Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.

Relic choice decides more runs in Slay the Spire 2 than almost any other purchase. This guide does not hand you a fixed S-to-D letter chart, because relic value depends on your deck. Instead it ranks all 296 relics by what they do, with priority rules you can apply on the fly.

How the priority tiers work

The tier is derived from the relic’s effect, not from opinion. The rules:

  • P1 — pick early. Grants energy, card draw, or Strength / Dexterity. These help every deck.
  • P2 — strong. Block, Thorns, Plating, or compounding “every turn / each combat” value.
  • P3 — situational. Gold, shops, healing, Max HP, or debuff auras. Good, not urgent.
  • P4 — niche. Tied to a specific card type or archetype (Strike, Sly, Doom, Summon).

Rarity is a separate axis. A Common relic that grants energy at combat start can outrank a Boss relic that only helps one archetype. Read the function first, the rarity second.

Relic tier list by function

Each table lists the relics in that function with their rarity, priority, and effect. Every name links to its full relic page.

Energy — 29 relics

Pick early. Universal, repeatable value that improves almost every deck.

RelicRarityPriorityEffect
Art of WarRare RelicP1If you do not play any Attacks during your turn, gain an additional 1 Energy next turn.
Blessed AntlerAncient RelicP1Gain 1 Energy at the start of each turn. At the start of each combat, shuffle 3 Dazed into your Draw Pile.
Blood-Soaked RoseAncient RelicP1Upon pickup, add 1 Enthralled to your Deck. Gain 1 Energy at the start of each turn.
Booming ConchAncient RelicP1At the start of Elite combats, draw 2 additional cards and gain 1 Energy.
BreadShop RelicP1At the start of your first turn, lose 2 Energy. At the start of all other turns, gain 1 Energy.
CandelabraUncommon RelicP1At the start of your 2nd turn, gain 2 Energy.
ChandelierRare RelicP1At the start of your 3rd turn, gain 3 Energy.
EctoplasmAncient RelicP1You can no longer gain Gold. Gain 1 Energy at the start of each turn.
Gremlin HornUncommon RelicP1Whenever an enemy dies, gain 1 Energy and draw 1 card.
Happy FlowerCommon RelicP1Every 3 turns, gain 1 Energy.
Happy Flower???Event RelicP1Every 5 turns, gain 1 Energy.
Ice CreamRare RelicP1Energy is now conserved between turns.
Intimidating HelmetRare RelicP1Whenever you play a card that costs 2 Energy or more, gain 4 Block.
Ivory TileRare RelicP1Whenever you play a card that costs 3 Energy or more, gain 1 Energy.
LanternCommon RelicP1Start each combat with an additional 1 Energy.
NunchakuUncommon RelicP1Every time you play 10 Attacks, gain 1 Energy.
Pael’s FleshAncient RelicP1Gain an additional 1 Energy at the start of your 3rd turn, and every turn after that.
Pael’s TearsAncient RelicP1If you end your turn with unspent 1 Energy, gain an additional 2 Energy next turn.
Philosopher’s StoneAncient RelicP1Gain 1 Energy at the start of each turn. ALL enemies start combat with 1 Strength.
Prismatic GemAncient RelicP1Gain 1 Energy at the start of each turn. Card rewards now contain cards from other colors.
Pumpkin CandleAncient RelicP1Gain 1 Energy at the start of each turn. Extinguishes after 5 combats. Can be Kindled at Rest Sites.
Seal of GoldAncient RelicP1At the start of your turn, spend 5 Gold to gain 1 Energy.
SozuAncient RelicP1Gain 1 Energy at the start of each turn. You can no longer obtain potions.
Spiked GauntletsAncient RelicP1Gain 1 Energy at the start of each turn. Powers cost 1 more 1 Energy.
Velvet ChokerAncient RelicP1Gain 1 Energy at the start of each turn. You cannot play more than 6 cards per turn.
Venerable Tea SetCommon RelicP1Whenever you enter a Rest Site, start the next combat with an additional 2 Energy.
Venerable Tea Set???Event RelicP1Whenever you enter a Rest Site, start the next combat with an additional 1 Energy.
Very Hot CocoaAncient RelicP1Start each combat with an additional 4 Energy.
Whispering EarringAncient RelicP1Gain 1 Energy at the start of each turn. Vakuu plays your first turn for you.

Card Draw — 25 relics

Pick early. Universal, repeatable value that improves almost every deck.

RelicRarityPriorityEffect
Bag of PreparationCommon RelicP1At the start of each combat, draw 2 additional cards.
BellowsRare RelicP1The first Hand you draw each combat is Upgraded.
Big MushroomEvent RelicP1Upon pickup, raise your Max HP by 20. At the start of each combat, draw 2 fewer cards.
Biiig HugAncient RelicP1Upon pickup, remove 4 cards from your Deck. Whenever you shuffle your Draw Pile, add a Soot into your Draw Pile.
Centennial PuzzleCommon RelicP1The first time you lose HP each combat, draw 3 cards.
FiddleAncient RelicP1At the start of each turn, draw 2 additional cards. You may not draw cards during your turn.
Funerary MaskUncommon RelicP1At the start of each combat, add 3 Souls into your Draw Pile.
Gambling ChipRare RelicP1At the start of each combat, discard any number of cards then draw that many.
Game PieceRare RelicP1Whenever you play a Power, draw 1 card.
Iron ClubAncient RelicP1Every 4 cards you play, draw 1 card.
Jeweled MaskAncient RelicP1At the start of each combat, put a random Power from your Draw Pile into your Hand. It’s free to play this combat.
Joss PaperUncommon RelicP1Every 5 times you Exhaust a card, draw 1 card.
Pael’s BloodAncient RelicP1At the start of your turn, draw 1 additional card.
PendulumCommon RelicP1Every 3 turns, draw 1 card.
PocketwatchRare RelicP1Whenever you play 3 or fewer cards during your turn, draw 3 additional cards at the start of your next turn.
Pollinous CoreEvent RelicP1Every 4 turns, draw 2 additional cards.
Power CellRare RelicP1At the start of each combat, add 2 zero-cost cards from your Draw Pile into your Hand.
Ring of the DrakeStarter RelicP1At the start of your first 3 turns, draw 2 additional cards.
Ring of the SnakeStarter RelicP1At the start of each combat, draw 2 additional cards.
Snecko EyeAncient RelicP1At the start of your turn, draw 2 additional cards. Start each combat Confused.
Stone CrackerUncommon RelicP1At the start of each combat, Upgrade 2 random cards in your Draw Pile for the rest of combat.
Tea of DiscourtesyEvent RelicP1At the start of the next combat, shuffle 2 Dazed into your Draw Pile.
The AbacusShop RelicP1Whenever you shuffle your Draw Pile, gain 6 Block.
Toasty MittensAncient RelicP1At the start of your turn, Exhaust the top card of your Draw Pile and gain 1 Strength.
Unceasing TopRare RelicP1Whenever you have no cards in Hand during your turn, draw a card.

Strength & Dexterity — 17 relics

Pick early. Universal, repeatable value that improves almost every deck.

RelicRarityPriorityEffect
Belt BuckleShop RelicP1While you have no potions, you have 2 additional Dexterity.
BrimstoneShop RelicP1At the start of your turn, gain 2 Strength and ALL enemies gain 1 Strength.
Ember TeaEvent RelicP1At the start of the next 5 combats, gain 2 Strength.
GiryaRare RelicP1You can now gain Strength at Rest Sites. (3 times max)
Helical DartRare RelicP1Whenever you play a Shiv, gain 1 Dexterity this turn.
KunaiRare RelicP1Every time you play 3 Attacks in a single turn, gain 1 Dexterity.
Mini RegentRare RelicP1The first time you spend 1 Stars each turn, gain 1 Strength.
Oddly Smooth StoneCommon RelicP1Start each combat with 1 Dexterity.
Rainbow RingRare RelicP1The first time you play an Attack, Skill, and Power each turn, gain 1 Strength and 1 Dexterity.
Red SkullCommon RelicP1While your HP is at or below 50%, you have 3 additional Strength.
Reptile TrinketUncommon RelicP1Whenever you use a potion, gain 3 Strength this turn.
Ruined HelmetRare RelicP1The first time you gain Strength each combat, double the amount gained.
ShurikenRare RelicP1Every time you play 3 Attacks in a single turn, gain 1 Strength.
Sling of CourageShop RelicP1Start each Elite combat with 2 Strength.
Sparkling RougeUncommon RelicP1At the start of your 3rd turn, gain 1 Strength and 1 Dexterity.
Sword of JadeEvent RelicP1Start each combat with 3 Strength.
VajraCommon RelicP1Start each combat with 1 Strength.

Block & Defense — 27 relics

Strong. Defensive, offensive, or deck-improving value that pays off across a run.

RelicRarityPriorityEffect
AnchorCommon RelicP2Start each combat with 10 Block.
Anchor???Event RelicP2Start each combat with 4 Block.
Bone FluteCommon RelicP2Whenever Osty attacks, gain 2 Block.
Bronze ScalesCommon RelicP2Start each combat with 3 Thorns.
Captain’s WheelRare RelicP2At the start of your 3rd turn, gain 18 Block.
Cloak ClaspRare RelicP2At the end of your turn, gain 1 Block for each card in your Hand.
Daughter of the WindEvent RelicP2Whenever you play an Attack, gain 1 Block.
Fresnel LensEvent RelicP2Whenever you add a card that gains Block to your Deck, Enchant it with Nimble 2.
Galactic DustUncommon RelicP2For every 10 1 Stars spent, gain 10 Block.
GorgetCommon RelicP2At the start of each combat, gain 4 Plating.
Hand DrillEvent RelicP2Whenever you break an enemy’s Block, apply 2 Vulnerable.
Horn CleatUncommon RelicP2At the start of your 2nd turn, gain 14 Block.
OrichalcumUncommon RelicP2If you end your turn without Block, gain 6 Block.
Orichalcum???Event RelicP2If you end your turn without Block, gain 3 Block.
Ornamental FanUncommon RelicP2Every time you play 3 Attacks in a single turn, gain 4 Block.
Pael’s LegionAncient RelicP2Doubles Block gained from a card, then goes to sleep for 2 turns.
Parrying ShieldUncommon RelicP2If you end a turn with at least 10 Block, deal 6 damage to a random enemy.
PermafrostUncommon RelicP2The first time you play a Power each combat, gain 7 Block.
RegaliteUncommon RelicP2Whenever you create a card, gain 2 Block.
Ripple BasinUncommon RelicP2If you did not play any Attacks during your turn, gain 4 Block.
SaiAncient RelicP2At the start of your turn, gain 7 Block.
Self-Forming ClayUncommon RelicP2Whenever you lose HP in combat, gain 3 Block next turn.
Sturdy ClampRare RelicP2Up to 10 Block persists across turns.
Tough BandagesRare RelicP2Whenever you discard a card during your turn, gain 3 Block.
Tuning ForkUncommon RelicP2Every time you play 10 Skills, gain 7 Block.
VambraceUncommon RelicP2The first time you gain Block from a card each combat, double the amount gained.
Vitruvian MinionShop RelicP2Cards containing “Minion” deal double damage and gain double Block.

Recurring Scaling — 41 relics

Strong. Defensive, offensive, or deck-improving value that pays off across a run.

RelicRarityPriorityEffect
AkabekoUncommon RelicP2At the start of each combat, gain 8 Vigor.
Bag of MarblesCommon RelicP2At the start of each combat, apply 1 Vulnerable to ALL enemies.
Big HatRare RelicP2At the start of each combat, add 2 random Ethereal cards into your Hand.
Blood VialCommon RelicP2At the start of each combat, heal 2 HP.
Blood Vial???Event RelicP2At the start of each combat, heal 1 HP.
Book of Five RingsCommon RelicP2Every 5 cards you add to your Deck, heal 20 HP.
BookmarkRare RelicP2At the end of each turn, lower the cost of a random Retained card by 1 until played.
Brilliant ScarfAncient RelicP2The 5th card you play from your hand each turn is free.
Burning SticksShop RelicP2The first time each combat you Exhaust a Skill, add a copy of it into your Hand.
Choices ParadoxAncient RelicP2At the start of each combat, add 1 of 5 random cards into your Hand. Add Retain to the chosen card.
Cracked CoreStarter RelicP2At the start of each combat, Channel 1 Lightning.
Data DiskCommon RelicP2Start each combat with 1 Focus.
Delicate FrondAncient RelicP2At the start of each combat, fill all empty potion slots with random potions.
Divine DestinyStarter RelicP2At the start of each combat, gain 6 Stars.
Divine RightStarter RelicP2At the start of each combat, gain 3 Stars.
Eternal FeatherUncommon RelicP2For every 5 cards in your Deck, heal 3 HP whenever you enter a Rest Site.
Fencing ManualCommon RelicP2At the start of each combat, Forge 10.
Festive PopperCommon RelicP2At the start of each combat, deal 9 damage to ALL enemies.
Fishing RodAncient RelicP2Every 3 normal combats, Upgrade a random card in your Deck.
Infused CoreStarter RelicP2At the start of each combat, Channel 3 Lightning. Lightning deals 1 additional damage.
MetronomeRare RelicP2The first time you Channel 7 Orbs each combat, deal 30 damage to ALL enemies.
Music BoxAncient RelicP2Create an Ethereal copy of the first Attack you play each turn.
Ninja ScrollShop RelicP2At the start of each combat, add 3 Shivs into your Hand.
Orange DoughRare RelicP2At the start of each combat, add 2 random Colorless cards into your Hand.
Pael’s EyeAncient RelicP2The first time each combat you end your turn without playing cards, Exhaust your Hand, and take an extra turn.
Pael’s ToothAncient RelicP2Upon pickup, remove 5 cards from your Deck. After each combat, randomly add 1 back Upgraded.
Pael’s WingAncient RelicP2You may sacrifice card rewards to Pael. Every 2 sacrifices, obtain a Relic.
Petrified ToadUncommon RelicP2At the start of each combat, procure a Potion-Shaped Rock.
Phylactery UnboundStarter RelicP2At the start of each combat, Summon 5. At the start of your turn, Summon 2.
Radiant PearlAncient RelicP2At the start of each combat, add 1 Luminesce into your Hand.
Red MaskCommon RelicP2At the start of each combat, apply 1 Weak to ALL enemies.
Royal PoisonEvent RelicP2At the start of each combat, lose 4 HP.
Runic CapacitorShop RelicP2Start each combat with 3 additional Orb Slots.
Snecko Eye???Event RelicP2Start each combat Confused.
Symbiotic VirusUncommon RelicP2At the start of each combat, Channel 1 Dark.
Throwing AxeAncient RelicP2The first card you play each combat is played an extra time.
ToolboxShop RelicP2At the start of each combat, choose 1 of 3 random Colorless cards and add the chosen card into your Hand.
Toy BoxAncient RelicP2Upon pickup, obtain 4 Wax Relics. Every 3 combats, your left-most Wax Relic will melt away.
Twisted FunnelUncommon RelicP2At the start of each combat, apply 4 Poison to ALL enemies.
Unsettling LampRare RelicP2Each combat, the first time you play a card that Debuffs an enemy, double its effect.
Vexing PuzzleboxRare RelicP2At the start of each combat, add a random card into your Hand. It’s free to play this turn.

Damage & AoE — 22 relics

Strong. Defensive, offensive, or deck-improving value that pays off across a run.

RelicRarityPriorityEffect
Charon’s AshesRare RelicP2Whenever you Exhaust a card, deal 3 damage to ALL enemies.
Diamond DiademAncient RelicP2Whenever you play 2 or fewer cards in a turn, take half damage from enemies.
Forgotten SoulEvent RelicP2Whenever you Exhaust a card, deal 1 damage to a random enemy.
KusarigamaUncommon RelicP2Every time you play 3 Attacks in a single turn, deal 6 damage to a random enemy.
Lava LampShop RelicP2At the end of combat, Upgrade all card rewards if you took no damage.
Letter OpenerUncommon RelicP2Every time you play 3 Skills in a single turn, deal 5 damage to ALL enemies.
Lost WispEvent RelicP2Whenever you play a Power, deal 8 damage to ALL enemies.
Mercury HourglassUncommon RelicP2At the start of your turn, deal 3 damage to ALL enemies.
Miniature CannonUncommon RelicP2Upgraded Attacks deal 3 additional damage.
Mr. StrugglesEvent RelicP2At the start of your turn, deal damage equal to the turn number to ALL enemies.
Mystic LighterShop RelicP2Enchanted Attacks deal 9 additional damage.
Paper KraneRare RelicP2Enemies with Weak deal 40% less damage to you rather than 25%.
Paper PhrogUncommon RelicP2Enemies with Vulnerable take 75% more damage rather than 50%.
Pen NibUncommon RelicP2Every 10th Attack you play deals double damage.
Screaming FlagonShop RelicP2If you end your turn with no cards in your Hand, deal 20 damage to ALL enemies.
Snecko SkullCommon RelicP2Whenever you apply Poison, apply an additional 1 Poison.
Stone CalendarRare RelicP2At the end of turn 7, deal 52 damage to ALL enemies.
Strike DummyCommon RelicP2Cards containing “Strike” deal 3 additional damage.
Strike Dummy???Event RelicP2Cards containing “Strike” deal 1 additional damage.
The BootEvent RelicP2Whenever you would deal 4 or less unblocked attack damage, increase it to 5.
TingshaUncommon RelicP2Whenever you discard a card during your turn, deal 3 damage to a random enemy for each card discarded.
Undying SigilShop RelicP2Enemies with at least as much Doom as HP deal 50% less damage.

Potions & Consumables — 4 relics

Situational. Economy, sustain, utility, or matchup value; good but not urgent.

RelicRarityPriorityEffect
Alchemical CofferAncient RelicP3Upon pickup, gain 4 potion slots filled with random potions.
Lost CofferAncient RelicP3Upon pickup, gain 1 card reward and procure 1 random potion.
Phial HolsterAncient RelicP3Upon pickup, gain 1 potion slot and procure 2 random potions.
Potion BeltCommon RelicP3Upon pickup, gain 2 potion slots.

Upgrade / Transform / Enchant — 31 relics

Strong. Defensive, offensive, or deck-improving value that pays off across a run.

RelicRarityPriorityEffect
Archaic ToothAncient RelicP2Upon pickup, Transform a starter card into an ancient version.
AstrolabeAncient RelicP2Upon pickup, Transform 3 cards, then Upgrade them.
Beautiful BraceletAncient RelicP2Upon pickup, choose 3 cards in your Deck. Enchant them with Swift 3.
Bone TeaEvent RelicP2At the start of the next combat, Upgrade your starting hand.
ClawsAncient RelicP2Upon pickup, Transform up to 6 cards into Maul.
Electric ShrympAncient RelicP2Upon pickup, Enchant a Skill with Imbued.
Fragrant MushroomEvent RelicP2Upon pickup, lose 15 HP and Upgrade 2 random cards.
Frozen EggRare RelicP2Whenever you add a Power into your Deck, Upgrade it.
GlitterAncient RelicP2Enchant all card rewards with Glam.
Gnarled HammerShop RelicP2Upon pickup, Enchant up to 3 Attacks with Sharp 3.
KifudaShop RelicP2Upon pickup, Enchant up to 3 cards with Adroit.
Leafy PoulticeAncient RelicP2Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose 12 Max HP.
Molten EggRare RelicP2Whenever you add an Attack card to your Deck, Upgrade it.
Neow’s TalismanAncient RelicP2Upon pickup, Upgrade 1 of your Strikes and 1 of your Defends.
New LeafAncient RelicP2Upon pickup, Transform 1 card.
Nutritious SoupAncient RelicP2Upon pickup, Enchant all Strikes in your Deck with Tezcatara’s Ember.
Pael’s ClawAncient RelicP2Upon pickup, Enchant all Defends with Goopy.
Pael’s GrowthAncient RelicP2Upon pickup, Enchant a card with Clone.
Pandora’s BoxAncient RelicP2Transform ALL Strikes and Defends.
PomanderAncient RelicP2Upon pickup, Upgrade a card.
Punch DaggerShop RelicP2Upon pickup, Enchant an Attack with Momentum 5.
Razor ToothRare RelicP2Every time you play an Attack or Skill, Upgrade it for the remainder of combat.
Royal StampShop RelicP2Upon pickup, choose an Attack or Skill in your Deck to Enchant with Royally Approved.
Sand CastleAncient RelicP2Upon pickup, Upgrade 6 random cards.
Silken TressAncient RelicP2Upon pickup, lose all Gold. Enchant all cards in the first card reward with Glam.
Toxic EggRare RelicP2Whenever you add a Skill into your Deck, Upgrade it.
Tri-BoomerangAncient RelicP2Choose 3 Attacks in your Deck. Enchant them with Instinct.
War HammerAncient RelicP2Whenever you kill an Elite, Upgrade 4 random cards.
War PaintCommon RelicP2Upon pickup, Upgrade 2 random Skills.
WhetstoneCommon RelicP2Upon pickup, Upgrade 2 random Attacks.
Yummy CookieAncient RelicP2Upon pickup, Upgrade 4 cards.

Orbs (Defect) — 1 relics

Strong. Defensive, offensive, or deck-improving value that pays off across a run.

RelicRarityPriorityEffect
Gold-Plated CablesUncommon RelicP2Your rightmost Orb triggers its passive an additional time.

Map & Rest Site — 8 relics

Situational. Economy, sustain, utility, or matchup value; good but not urgent.

RelicRarityPriorityEffect
Dream CatcherEvent RelicP3Whenever you Rest, you may add a card to your Deck.
Golden CompassAncient RelicP3Upon pickup, replace the Act 2 Map with a single special path.
Meat CleaverAncient RelicP3You may Cook at Rest Sites.
Miniature TentShop RelicP3You may choose any number of options at Rest Sites.
Regal PillowCommon RelicP3Whenever you Rest, heal an additional 15 HP.
ShovelRare RelicP3You can now dig at Rest Sites to obtain a random Relic.
Stone HumidifierAncient RelicP3Whenever you Rest at a Rest Site, raise your Max HP by 5.
Tiny MailboxUncommon RelicP3Whenever you Rest, procure 2 random potions.

Gold & Shops — 13 relics

Situational. Economy, sustain, utility, or matchup value; good but not urgent.

RelicRarityPriorityEffect
Amethyst AubergineCommon RelicP3Enemies drop 15 additional Gold.
Bowler HatUncommon RelicP3Gain 25% additional Gold.
Cursed PearlAncient RelicP3Upon pickup, receive Greed. Gain 333 Gold.
Dragon FruitShop RelicP3Whenever you gain Gold, raise your Max HP by 1.
Golden PearlAncient RelicP3Upon pickup, gain 150 Gold.
Lord’s ParasolAncient RelicP3When you encounter the Merchant, immediately obtain EVERYTHING he sells.
Lucky FyshUncommon RelicP3Whenever you add a card to your Deck, gain 15 Gold.
Maw BankEvent RelicP3Whenever you climb a floor, gain 12 Gold. No longer works when you spend any Gold at the shop.
Meal TicketCommon RelicP3Whenever you enter a shop room, heal 15 HP.
Membership CardShop RelicP350% discount on all products!
Old CoinRare RelicP3Upon pickup, gain 300 Gold.
Signet RingAncient RelicP3Upon pickup, gain 999 Gold.
The CourierRare RelicP3The merchant no longer runs out of cards, relics, or potions and his prices are reduced by 20%.

Heal & Max HP — 19 relics

Situational. Economy, sustain, utility, or matchup value; good but not urgent.

RelicRarityPriorityEffect
Black BloodStarter RelicP3At the end of combat, heal 12 HP.
Book Repair KnifeUncommon RelicP3Whenever a non-Minion enemy dies to Doom, heal 3 HP.
Burning BloodStarter RelicP3At the end of combat, heal 6 HP.
Darkstone PeriaptEvent RelicP3Whenever you obtain a Curse, raise your Max HP by 6.
Demon TongueRare RelicP3The first time you lose HP on your turn, heal HP equal to the amount lost.
Distinguished CapeAncient RelicP3Upon pickup, lose 9 Max HP. Add 3 Apparitions to your Deck.
Lee’s WaffleShop RelicP3Upon pickup, raise your Max HP by 7 and heal all of your HP.
Lee’s Waffle???Event RelicP3Upon pickup, heal 10% of your HP.
Lizard TailRare RelicP3When your HP would be reduced to 0, heal to 50% of your Max HP instead (works once).
Looming FruitAncient RelicP3Upon pickup, raise your Max HP by 31.
MangoRare RelicP3Upon pickup, raise your Max HP by 14.
Mango???Event RelicP3Upon pickup, raise your Max HP by 3.
Meat on the BoneRare RelicP3If your HP is at or below 50% at the end of combat, heal 12 HP.
Nutritious OysterAncient RelicP3Upon pickup, raise your Max HP by 11.
PantographUncommon RelicP3At the start of each Boss combat, heal 25 HP.
PearUncommon RelicP3Upon pickup, raise your Max HP by 10.
PlanisphereUncommon RelicP3Whenever you enter a ? room, heal 5 HP.
StrawberryCommon RelicP3Upon pickup, raise your Max HP by 7.
The Chosen CheeseEvent RelicP3At the end of combat, gain 1 Max HP.

Archetype / Card-type — 4 relics

Niche. Depends on a specific archetype or card type to shine.

RelicRarityPriorityEffect
Bound PhylacteryStarter RelicP4At the start of your turn, Summon 1.
Calling BellAncient RelicP4Upon pickup, obtain a unique Curse and 3 Relics.
Large CapsuleAncient RelicP4Upon pickup, obtain 2 random Relics. Add an additional Strike and Defend to your Deck.
Neow’s BonesAncient RelicP4Upon pickup, gain 2 random Neow Relics. Add 1 random Curse to your Deck.

Other / Utility — 55 relics

Situational. Economy, sustain, utility, or matchup value; good but not urgent.

RelicRarityPriorityEffect
Arcane ScrollAncient RelicP3Upon pickup, obtain a random Rare Card to add to your Deck.
Beating RemnantRare RelicP3You cannot lose more than 20 HP in a single turn.
Bing BongEvent RelicP3Whenever you add a card to your Deck, add one additional copy.
Black StarAncient RelicP3Elites drop an additional Relic when defeated.
ByrdpipEvent RelicP3Upon pickup, gain the card Byrd Swoop. A Byrdpip will accompany you in battles.
CauldronShop RelicP3Upon pickup, brews 5 random potions.
Chemical XShop RelicP3The effects of your cost X cards are increased by 2.
CircletRelicP3It’s a circlet.
CrossbowAncient RelicP3At the start of your turn, add a random Attack into your Hand. It’s free to play this turn.
Dingy RugShop RelicP3Card rewards can now contain Colorless cards.
Dolly’s MirrorShop RelicP3Upon pickup, obtain an additional copy of a card in your Deck.
DriftwoodAncient RelicP3You may reroll each card reward once.
Dusty TomeAncient RelicP3Upon pickup, obtain an Ancient Card.
Emotion ChipRare RelicP3If you lost HP during the previous turn, trigger the passive ability of all Orbs at the start of your turn.
Empty CageAncient RelicP3Upon pickup, remove 2 cards from your Deck.
Fur CoatAncient RelicP3Upon pickup, mark 7 random combats. Enemies in those rooms have 1 HP.
Ghost SeedShop RelicP3Strikes and Defends gain Ethereal.
Glass EyeAncient RelicP3Upon pickup, obtain 2 Common cards, 2 Uncommon cards, and 1 Rare card.
Hefty TabletAncient RelicP3Upon pickup, choose 1 of 3 Rare cards to add to your Deck, and add 1 Injury to your Deck.
History CourseEvent RelicP3At the start of your turn, play a copy of your last played Attack or Skill.
Jewelry BoxAncient RelicP3Upon pickup, add 1 Apotheosis to your Deck.
Juzu BraceletCommon RelicP3Regular enemy combats are no longer encountered in ? rooms.
KaleidoscopeAncient RelicP3Upon pickup, obtain 2 card rewards from other characters.
Lasting CandyUncommon RelicP3Every other combat, your card rewards gain an additional Power.
Lava RockAncient RelicP3The Act 1 Boss drops 2 Relics.
Lead PaperweightAncient RelicP3Upon pickup, choose 1 of 2 Colorless cards to add to your Deck.
Lunar PastryRare RelicP3At the end of your turn, gain 1 Stars.
Massive ScrollAncient RelicP3Upon pickup, choose 1 of 3 Multiplayer Cards to add to your Deck.
Mummified HandRare RelicP3Whenever you play a Power, a random card in your Hand is free to play that turn.
Neow’s TormentAncient RelicP3Upon pickup, add 1 Neow’s Fury to your Deck.
OrreryShop RelicP3Upon pickup, gain 5 card rewards.
Pael’s HornAncient RelicP3Upon pickup, add 2 Relax to your Deck.
Prayer WheelRare RelicP3Normal enemies drop an additional card reward.
Precarious ShearsAncient RelicP3Upon pickup, remove 2 cards from your Deck and lose 16 HP.
Precise ScissorsAncient RelicP3Upon pickup, remove 1 card from your Deck.
Preserved FogAncient RelicP3Upon pickup, remove 3 cards from your Deck. Add Folly to your Deck.
Ringing TriangleShop RelicP3Retain your Hand on the first turn of combat.
Runic PyramidAncient RelicP3At the end of your turn, you no longer discard your Hand.
Scroll BoxesAncient RelicP3Upon pickup, choose 1 of 2 packs of cards to add to your Deck.
Sea GlassAncient RelicP3See 15 cards from another character. Choose any number of them to add to your Deck.
Sere TalonAncient RelicP3Upon pickup, add 2 random Curses and 3 Wishes to your Deck.
Silver CrucibleAncient RelicP3The first 3 card rewards you see are Upgraded. The first Treasure Chest you open is empty.
Small CapsuleAncient RelicP3Upon pickup, obtain a random Relic.
StorybookAncient RelicP3Upon pickup, add 1 Brightest Flame to your Deck.
Sword of StoneEvent RelicP3Transforms into a powerful Relic after defeating 5 Elites.
Tanx’s WhistleAncient RelicP3Upon pickup, add 1 Whistle to your Deck.
The Merchant’s Rug???Event RelicP3Poor imitation. Does nothing.
Touch of OrobasAncient RelicP3Upon pickup, replace your starter Relic with an Ancient version.
Tungsten RodRare RelicP3Whenever you would lose HP, lose 1 less.
White Beast StatueRare RelicP3Potions always appear in combat rewards.
White StarRare RelicP3Elites drop an additional Rare card reward.
Wing CharmShop RelicP3A random card in each card reward is Enchanted with Swift 1.
Winged BootsAncient RelicP3You may ignore paths when choosing the next rooms to travel to 3 times.
Wongo Customer Appreciation BadgeEvent RelicP3Does nothing.
Wongo’s Mystery TicketEvent RelicP3Receive 3 random Relics after 5 combats.

Best relics by character

Some relics are locked to one character by their pool. If you are learning a character, start with the relics listed under its name. The pools below only show characters that have at least one locked relic in the current build.

Ironclad — 9 locked relic(s)

RelicPriorityEffect
Red SkullP1While your HP is at or below 50%, you have 3 additional Strength.
Ruined HelmetP1The first time you gain Strength each combat, double the amount gained.
BrimstoneP1At the start of your turn, gain 2 Strength and ALL enemies gain 1 Strength.
Paper PhrogP2Enemies with Vulnerable take 75% more damage rather than 50%.
Self-Forming ClayP2Whenever you lose HP in combat, gain 3 Block next turn.
Charon’s AshesP2Whenever you Exhaust a card, deal 3 damage to ALL enemies.
Black BloodP3At the end of combat, heal 12 HP.
Burning BloodP3At the end of combat, heal 6 HP.
Demon TongueP3The first time you lose HP on your turn, heal HP equal to the amount lost.

Necrobinder — 9 locked relic(s)

RelicPriorityEffect
Funerary MaskP1At the start of each combat, add 3 Souls into your Draw Pile.
Ivory TileP1Whenever you play a card that costs 3 Energy or more, gain 1 Energy.
Phylactery UnboundP2At the start of each combat, Summon 5. At the start of your turn, Summon 2.
Bone FluteP2Whenever Osty attacks, gain 2 Block.
Big HatP2At the start of each combat, add 2 random Ethereal cards into your Hand.
BookmarkP2At the end of each turn, lower the cost of a random Retained card by 1 until played.
Undying SigilP2Enemies with at least as much Doom as HP deal 50% less damage.
Book Repair KnifeP3Whenever a non-Minion enemy dies to Doom, heal 3 HP.
Bound PhylacteryP4At the start of your turn, Summon 1.

Defect — 9 locked relic(s)

RelicPriorityEffect
Power CellP1At the start of each combat, add 2 zero-cost cards from your Draw Pile into your Hand.
Cracked CoreP2At the start of each combat, Channel 1 Lightning.
Infused CoreP2At the start of each combat, Channel 3 Lightning. Lightning deals 1 additional damage.
Data DiskP2Start each combat with 1 Focus.
Gold-Plated CablesP2Your rightmost Orb triggers its passive an additional time.
Symbiotic VirusP2At the start of each combat, Channel 1 Dark.
MetronomeP2The first time you Channel 7 Orbs each combat, deal 30 damage to ALL enemies.
Runic CapacitorP2Start each combat with 3 additional Orb Slots.
Emotion ChipP3If you lost HP during the previous turn, trigger the passive ability of all Orbs at the start of your turn.

Regent — 9 locked relic(s)

RelicPriorityEffect
Mini RegentP1The first time you spend 1 Stars each turn, gain 1 Strength.
Divine DestinyP2At the start of each combat, gain 6 Stars.
Divine RightP2At the start of each combat, gain 3 Stars.
Fencing ManualP2At the start of each combat, Forge 10.
Galactic DustP2For every 10 1 Stars spent, gain 10 Block.
RegaliteP2Whenever you create a card, gain 2 Block.
Orange DoughP2At the start of each combat, add 2 random Colorless cards into your Hand.
Vitruvian MinionP2Cards containing “Minion” deal double damage and gain double Block.
Lunar PastryP3At the end of your turn, gain 1 Stars.

Silent — 9 locked relic(s)

RelicPriorityEffect
Ring of the DrakeP1At the start of your first 3 turns, draw 2 additional cards.
Ring of the SnakeP1At the start of each combat, draw 2 additional cards.
Helical DartP1Whenever you play a Shiv, gain 1 Dexterity this turn.
Snecko SkullP2Whenever you apply Poison, apply an additional 1 Poison.
TingshaP2Whenever you discard a card during your turn, deal 3 damage to a random enemy for each card discarded.
Twisted FunnelP2At the start of each combat, apply 4 Poison to ALL enemies.
Paper KraneP2Enemies with Weak deal 40% less damage to you rather than 25%.
Tough BandagesP2Whenever you discard a card during your turn, gain 3 Block.
Ninja ScrollP2At the start of each combat, add 3 Shivs into your Hand.

Frequently asked questions

What is the best relic in Slay the Spire 2?

There is no single best relic. Energy, card draw, and Strength or Dexterity relics are the highest priority because they help every deck. The relic tier list below ranks by function, not by a fixed letter.

Are rarer relics always better?

Not always. Rarity tracks how often a relic appears, not its power. Some Common relics that grant energy or block at combat start outrank many Boss relics for early picks.

How should I read the priority tiers?

P1 means pick it in almost any run. P2 is strong defensive or scaling value. P3 is situational economy or sustain. P4 only matters for a specific archetype.

Should I skip a relic for deck space?

Relics do not take deck space, so you almost always take one when offered. The real choice is which shop relic to buy when you cannot afford all of them — use the priority tiers above.

Where do relic effects come from?

Every effect on this page is pulled from the official STS2 data API (spire-codex.com) on 17 October 2026. Numbers may shift as the game leaves early access.

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.