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Doom in Slay the Spire 2: All 13 Necrobinder Cards Listed

Updated 17 Oct 2026 Source Slay the Spire 2 card data (spire-codex.com API), 577 cards retrieved 17 October 2026 By
Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.

What Doom does

Doom is a stack you build on an enemy, not on yourself. Thirteen Necrobinder cards apply it.

Time’s Up is the cleanest payoff. It deals damage equal to the Doom already sitting on the target, so everything you spent earlier converts at once.

That is why spreading Doom across a room is wasteful. The card that cashes it in wants one large number, not three small ones.

Every card that uses Doom

These thirteen are the whole Doom line. The costs run from 0 to 3 Energy, and the amounts scale with the card.

CardCostEffectUpgraded
Blight Strike1 EnergyDeal 8 damage.; Apply Doom equal to damage dealt.Deal 10 damage.; Apply Doom equal to damage dealt.
Countdown1 EnergyAt the start of your turn, apply 6 Doom to a random enemy.At the start of your turn, apply 9 Doom to a random enemy.
Death’s Door1 EnergyGain 6 Block.; If you applied Doom this turn, gain Block 2 additional times.Gain 7 Block.; If you applied Doom this turn, gain Block 2 additional times.
Deathbringer2 EnergyApply 21 Doom and 1 Weak to ALL enemies.Apply 26 Doom and 1 Weak to ALL enemies.
End of Days3 EnergyApply 29 Doom to ALL enemies.; Kill enemies with at least as much Doom as HP.Apply 37 Doom to ALL enemies.; Kill enemies with at least as much Doom as HP.
Negative Pulse1 EnergyGain 5 Block.; Apply 7 Doom to ALL enemies.Gain 6 Block.; Apply 11 Doom to ALL enemies.
Neurosurge0 EnergyGain 3 Energy.; Draw 2 cards.; At the start of your turn, apply 3 Doom to yourself.Gain 4 Energy.; Draw 2 cards.; At the start of your turn, apply 3 Doom to yourself.
No Escape1 EnergyApply 10 Doom, plus an additional 5 Doom for every 10 Doom already on this enemy.Apply 15 Doom, plus an additional 5 Doom for every 10 Doom already on this enemy.
Oblivion0 EnergyWhenever you play a card this turn, apply 3 Doom to the enemy.Whenever you play a card this turn, apply 4 Doom to the enemy.
Reaper Form3 EnergyWhenever Attacks deal damage, apply that much Doom.-
Scourge1 EnergyApply 13 Doom.; Draw 1 card.Apply 16 Doom.; Draw 2 cards.
Shroud1 EnergyWhenever you apply Doom, gain 2 Block.Whenever you apply Doom, gain 3 Block.
Time’s Up2 EnergyDeal damage equal to the enemy’s Doom.-

Reading the amounts

Deathbringer applies 21 Doom to every enemy, and End of Days applies 29. Those are the two room-wide plays.

Oblivion and Reaper Form convert your whole turn into Doom. Oblivion adds 3 for each card you play, and Reaper Form applies Doom equal to the damage your attacks deal.

Countdown and Neurosurge do it without spending cards. Both apply Doom at the start of your turn, which keeps the stack growing while you do something else.

What supports it

Shroud turns Doom into Block, gaining 2 Block every time you apply it. Death’s Door does the same behind a condition, giving 6 Block and a bonus if you applied Doom that turn.

Those two are the defensive half. The rest of the list is pure stacking.

Where to go next

Necrobinder minions covers Osty, who holds the line while Doom builds. Necrobinder guide covers the rest of her pool.

Frequently asked questions

What does Doom do in Slay the Spire 2?

Doom stacks on an enemy. Time's Up then deals damage equal to the Doom on that target, which is how you convert the stack.

How many cards apply Doom?

Thirteen, all Necrobinder cards. They range from 0 to 3 Energy.

Which card applies the most Doom at once?

End of Days applies 29 Doom to every enemy. Deathbringer applies 21 plus 1 Weak to all enemies.

Does Doom hurt the Necrobinder?

No. It sits on enemies. Two cards, Shroud and Death's Door, turn applying it into Block for you.

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.