There are 63 Potions in Slay the Spire 2. The real question is never “what exists” but “which one fits the situation you are in” — so this page lays the full set out with the numbers that actually decide a pick, grouped so you can jump straight to the cluster that matches your run.
The full Potions list
| Name | Rarity | Notes |
|---|---|---|
| Ashwater | Uncommon | [gold]Exhaust[/gold] any number of cards in your [gold]Hand[/gold]. |
| Attack Potion | Common | Choose [blue]1[/blue] of [blue]3[/blue] random Attack cards to add into your [gold]Hand[/gold]. It’s free to play this |
| Beetle Juice | Rare | Enemy’s attacks deal [blue]30%[/blue] less damage for the next [blue]4[/blue] turns. |
| Blessing of the Forge | Uncommon | [gold]Upgrade[/gold] all cards in your [gold]Hand[/gold] for the rest of combat. |
| Block Potion | Common | Gain [blue]12[/blue] [gold]Block[/gold]. |
| Blood Potion | Common | Heal for [green]20%[/green] of your Max HP. |
| Bone Brew | Uncommon | [gold]Summon[/gold] [blue]15[/blue]. |
| Bottled Potential | Rare | Shuffle ALL your cards into your [gold]Draw Pile[/gold]. Draw [blue]5[/blue] cards. |
| Clarity Extract | Uncommon | Draw [blue]1[/blue] card. At the start of your next [blue]3[/blue] turns, draw [blue]1[/blue] additional card. |
| Colorless Potion | Common | Choose [blue]1[/blue] of [blue]3[/blue] random Colorless cards to add into your [gold]Hand[/gold]. It’s free to play |
| Cosmic Concoction | Rare | Add [blue]3[/blue] [gold]Upgraded[/gold] Colorless cards into your [gold]Hand[/gold]. |
| Cunning Potion | Uncommon | Add [blue]3[/blue] [gold]Upgraded Shivs[/gold] into your [gold]Hand[/gold]. |
| Cure All | Uncommon | Gain [energy:1]. Draw [blue]2[/blue] cards. |
| Dexterity Potion | Common | Gain [blue]2[/blue] [gold]Dexterity[/gold]. |
| Distilled Chaos | Rare | Play the top [blue]3[/blue] cards of your [gold]Draw Pile[/gold]. |
| Droplet of Precognition | Rare | Choose a card in your [gold]Draw Pile[/gold] and add it into your [gold]Hand[/gold]. |
| Duplicator | Uncommon | This turn, your next card is played an extra time. |
| Energy Potion | Common | Gain [energy:2]. |
| Entropic Brew | Rare | Fill all your empty potion slots with random potions. |
| Essence of Darkness | Rare | [gold]Channel[/gold] a [gold]Dark[/gold] for each of your [gold]Orb Slots[/gold]. |
| Explosive Ampoule | Common | Deal [blue]10[/blue] damage to ALL enemies. |
| Fairy in a Bottle | Rare | When your HP would be reduced to [blue]0[/blue], instead this potion is discarded and you heal to [blue]30%[/blue] of |
| Fire Potion | Common | Deal [blue]20[/blue] damage. |
| Flex Potion | Common | Gain [blue]5[/blue] [gold]Strength[/gold]. At the end of your turn, lose [blue]5[/blue] [gold]Strength[/gold]. |
| Focus Potion | Common | Gain [blue]2[/blue] [gold]Focus[/gold]. |
| Fortifier | Uncommon | Triple your [gold]Block[/gold]. |
| Foul Potion | Event | Deal [blue]12[/blue] damage to ALL players and enemies. Can be thrown at the [gold]Merchant[/gold] for [blue]100[/blue] |
| Fruit Juice | Rare | Gain [blue]5[/blue] Max HP. |
| Fysh Oil | Uncommon | Gain [blue]1[/blue] [gold]Strength[/gold] and [blue]1[/blue] [gold]Dexterity[/gold]. |
| Gambler’s Brew | Uncommon | Discard any number of cards, then draw that many. |
| Ghost in a Jar | Rare | Gain [blue]1[/blue] [gold]Intangible[/gold]. |
| Gigantification Potion | Rare | The next Attack you play deals triple damage. |
| Glowwater Potion | Event | [gold]Exhaust[/gold] your [gold]Hand[/gold]. Draw [blue]10[/blue] cards. |
| Heart of Iron | Uncommon | Gain [blue]7[/blue] [gold]Plating[/gold]. |
| King’s Courage | Uncommon | [gold]Forge[/gold] [blue]15[/blue]. |
| Liquid Bronze | Uncommon | Gain [blue]3[/blue] [gold]Thorns[/gold]. |
| Liquid Memories | Rare | Put a card from your [gold]Discard Pile[/gold] into your [gold]Hand[/gold]. It’s free to play this turn. |
| Lucky Tonic | Rare | Gain [blue]1[/blue] [gold]Buffer[/gold]. |
| Mazaleth’s Gift | Rare | Gain [blue]1[/blue] [gold]Ritual[/gold]. |
| Orobic Acid | Rare | Add a random Attack, Skill, and Power into your [gold]Hand[/gold]. They’re free to play this turn. |
| Poison Potion | Common | Apply [blue]6[/blue] [gold]Poison[/gold]. |
| Pot of Ghouls | Rare | Add [blue]2[/blue] [gold]Souls[/gold] into your [gold]Hand[/gold]. |
| Potion of Binding | Uncommon | Apply [blue]1[/blue] [gold]Weak[/gold] and [blue]1[/blue] [gold]Vulnerable[/gold] to ALL enemies. |
| Potion of Capacity | Uncommon | Gain [blue]2[/blue] [gold]Orb Slots[/gold]. |
| Potion of Doom | Common | Apply [blue]33[/blue] [gold]Doom[/gold]. |
| Potion-Shaped Rock | Token | Deal [blue]15[/blue] damage. |
| Powdered Demise | Uncommon | Enemy loses [blue]9[/blue] HP at the end of each of its turns. |
| Power Potion | Common | Choose [blue]1[/blue] of [blue]3[/blue] random Power cards to add into your [gold]Hand[/gold]. It’s free to play this |
| Radiant Tincture | Uncommon | Gain [energy:1]. Gain an additional [energy:1] at the start of your next [blue]3[/blue] turns. |
| Regen Potion | Uncommon | Gain [green]5[/green] [gold]Regen[/gold]. |
| Shackling Potion | Rare | ALL enemies lose [blue]7[/blue] [gold]Strength[/gold] this turn. |
| Ship in a Bottle | Rare | Gain [blue]10[/blue] [gold]Block[/gold]. Next turn, gain [blue]10[/blue] [gold]Block[/gold]. |
| Skill Potion | Common | Choose [blue]1[/blue] of [blue]3[/blue] random Skill cards to add into your [gold]Hand[/gold]. It’s free to play this |
| Snecko Oil | Rare | Draw [blue]7[/blue] cards. Randomize the cost of cards in your [gold]Hand[/gold] this turn. |
| Soldier’s Stew | Rare | All cards containing [gold]Strike[/gold] gain [blue]1[/blue] [gold]Replay[/gold] this combat. |
| Speed Potion | Common | Gain [blue]5[/blue] [gold]Dexterity[/gold]. At the end of your turn, lose [blue]5[/blue] [gold]Dexterity[/gold]. |
| Stable Serum | Uncommon | [gold]Retain[/gold] your [gold]Hand[/gold] for [blue]2[/blue] turns. |
| Star Potion | Common | Gain [star:3]. |
| Strength Potion | Common | Gain [blue]2[/blue] [gold]Strength[/gold]. |
| Swift Potion | Common | Draw [blue]3[/blue] cards. |
| Touch of Insanity | Uncommon | Choose a card in your [gold]Hand[/gold]. It is free to play this combat. |
| Vulnerable Potion | Common | Apply [blue]3[/blue] [gold]Vulnerable[/gold]. |
| Weak Potion | Common | Apply [blue]3[/blue] [gold]Weak[/gold]. |
How the Potions split by Rarity
Uncommon (20)
Ashwater — [gold]Exhaust[/gold] any number of cards in your [gold]Hand[/gold].. Blessing of the Forge — [gold]Upgrade[/gold] all cards in your [gold]Hand[/gold] for the rest of combat.. Bone Brew — [gold]Summon[/gold] [blue]15[/blue]..
Common (20)
Attack Potion — Choose [blue]1[/blue] of [blue]3[/blue] random Attack cards to add into your [gold]Hand[/gold]. It’s free to. Block Potion — Gain [blue]12[/blue] [gold]Block[/gold].. Blood Potion — Heal for [green]20%[/green] of your Max HP..
Rare (20)
Beetle Juice — Enemy’s attacks deal [blue]30%[/blue] less damage for the next [blue]4[/blue] turns.. Bottled Potential — Shuffle ALL your cards into your [gold]Draw Pile[/gold]. Draw [blue]5[/blue] cards.. Cosmic Concoction — Add [blue]3[/blue] [gold]Upgraded[/gold] Colorless cards into your [gold]Hand[/gold]..
Event (2)
Foul Potion — Deal [blue]12[/blue] damage to ALL players and enemies. Can be thrown at the [gold]Merchant[/gold] for. Glowwater Potion — [gold]Exhaust[/gold] your [gold]Hand[/gold]. Draw [blue]10[/blue] cards..
Token (1)
Potion-Shaped Rock — Deal [blue]15[/blue] damage..
The numbers at a glance
| Metric | Value |
|---|---|
| Total Potions tracked | 63 |
| With a written description | 62 |
| Without a written description | 1 |
| Uncommon — Rarity | 20 |
| Common — Rarity | 20 |
| Rare — Rarity | 20 |
| Event — Rarity | 2 |
| Token — Rarity | 1 |
What the Potions data tells us
If you only remember one thing: the rarity split is the fastest way to narrow 63 Potions down. Uncommon is the largest group at 20 entries, so start your comparison there before looking at anything else. Note: 1 of the 63 entries have no written description in the source data — for those you are reading stats only, so trust the numbers, not assumptions.
Entries worth a closer look
Foul Potion — Deal [blue]12[/blue] damage to ALL players and enemies. Can be thrown at the [gold]Merchant[/gold] for [blue]100[/blue] [gold]Gold[/gold] instead. Fairy in a Bottle — When your HP would be reduced to [blue]0[/blue], instead this potion is discarded and you heal to [blue]30%[/blue] of your Max HP. Colorless Potion — Choose [blue]1[/blue] of [blue]3[/blue] random Colorless cards to add into your [gold]Hand[/gold]. It’s free to play this turn. Attack Potion — Choose [blue]1[/blue] of [blue]3[/blue] random Attack cards to add into your [gold]Hand[/gold]. It’s free to play this turn. Power Potion — Choose [blue]1[/blue] of [blue]3[/blue] random Power cards to add into your [gold]Hand[/gold]. It’s free to play this turn. Skill Potion — Choose [blue]1[/blue] of [blue]3[/blue] random Skill cards to add into your [gold]Hand[/gold]. It’s free to play this turn. Speed Potion — Gain [blue]5[/blue] [gold]Dexterity[/gold]. At the end of your turn, lose [blue]5[/blue] [gold]Dexterity[/gold].
As the source data describes one entry: “[gold]Exhaust[/gold] any number of cards in your [gold]Hand[/gold].”