Soul Nexus — Elite in Slay the Spire 2

Updated 17 Oct 2026 Source Slay the Spire 2 enemy data (spire-codex.com API), 115 enemies retrieved 17 October 2026 By Antewise Editorial

Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.

Soul Nexus is a Elite enemy with 234 (Ascension 254) HP in Slay the Spire 2.

Type	Elite
HP	234 (Ascension 254)

Move set

Move	Intent	Damage	Block	Heal
Soul Burn	Attack	29 / Asc 31	—	—
Maelstrom	Attack	24 (6×4=24) / Asc 28 (7×4=28)	—	—
Drain Life	Attack + Debuff	18 / Asc 19	—	—

Attack pattern

This enemy uses a random pattern , starting with SOUL_BURN. The documented sequence is: SOUL_BURN → MAELSTROM → DRAIN_LIFE → RAND → RAND.

Where it appears

Act 3 - Glory — Elite

Other Elite enemies

Bygone Effigy — Elite
Byrdonis — Elite
Decimillipede — Elite
Entomancer — Elite
Flail Knight — Elite
Infested Prism — Elite
Magi Knight — Elite
Mecha Knight — Elite
Phantasmal Gardener — Elite
Phrog Parasite — Elite

Where to go next

All 115 enemies — the full list. Card database lists the tools you bring to the fight.

Relics cover the passive bonuses that help you survive. Boss guide hub explains the named fights.

Frequently asked questions

What is Soul Nexus in Slay the Spire 2?

Soul Nexus is a Elite enemy with 234 (Ascension 254) HP. Its moves and attack pattern are listed below.

Where does Soul Nexus appear?

It appears in: Act 3 - Glory.

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.