Antewise

Queen — Boss in Slay the Spire 2

Updated 17 Oct 2026 Source Slay the Spire 2 enemy data (spire-codex.com API), 115 enemies retrieved 17 October 2026 By
Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.
Queen art
Queen

Queen is a Boss enemy with 400 (Ascension 419) HP in Slay the Spire 2.

TypeBoss
HP400 (Ascension 419)

Move set

MoveIntentDamageBlockHeal
Puppet Strings Debuff — — —
You Are Mine Debuff — — —
Burn Bright for Me Buff + Defend — 20 —
Off with Your Head Attack 15 (3×5=15) / Asc 20 (4×5=20) — —
Execution Attack 15 / Asc 18 — —
Enrage Buff — — —

Attack pattern

This enemy uses a conditional pattern , starting with PUPPET_STRINGS. The documented sequence is: PUPPET_STRINGS → YOU_ARE_MINE → OFF_WITH_YOUR_HEAD → EXECUTION → BURN_BRIGHT_FOR_ME → ENRAGE → YOURE_MINE_NOW_BRANCH → BURN_BRIGHT_FOR_ME_BRANCH.

Where it appears

  • Act 3 - Glory — Boss

Quotes

  • “[object Object]”
  • “[object Object]”

Other Boss enemies

Where to go next

All 115 enemies — the full list. Card database lists the tools you bring to the fight.

Relics cover the passive bonuses that help you survive. Boss guide hub explains the named fights.

Frequently asked questions

What is Queen in Slay the Spire 2?

Queen is a Boss enemy with 400 (Ascension 419) HP. Its moves and attack pattern are listed below.

Where does Queen appear?

It appears in: Act 3 - Glory.

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.