Louse Progenitor — Normal in Slay the Spire 2

Updated 17 Oct 2026 Source Slay the Spire 2 enemy data (spire-codex.com API), 115 enemies retrieved 17 October 2026 By Antewise Editorial

Data status: The facts on this page were checked against the source named above. Game values can still shift with a patch, so re-check anything that looks off.

Louse Progenitor is a Normal enemy with 134–136 (Ascension 138–141) HP in Slay the Spire 2.

Type	Normal
HP	134–136 (Ascension 138–141)
Innate powers	CURL_UP 14

Move set

Move	Intent	Damage	Block	Heal
Web Cannon	Attack + Debuff	9 / Asc 10	—	—
Pounce	Attack	14 / Asc 16	—	—
Curl and Grow	Defend + Buff	—	14	—

Attack pattern

This enemy uses a cycle pattern , starting with WEB_CANNON. The documented sequence is: WEB_CANNON → POUNCE → CURL_AND_GROW.

Where it appears

Act 2 - Hive — Monster

Other Normal enemies

The Architect — Normal
Assassin Raider — Normal
Axe Raider — Normal
Axebot — Normal
Battle Friend V1.0 — Normal
Battle Friend V2.0 — Normal
Battle Friend V3.0 — Normal
Bowlbug (Egg) — Normal
Bowlbug (Nectar) — Normal
Bowlbug (Rock) — Normal

Where to go next

All 115 enemies — the full list. Card database lists the tools you bring to the fight.

Relics cover the passive bonuses that help you survive. Boss guide hub explains the named fights.

Frequently asked questions

What is Louse Progenitor in Slay the Spire 2?

Louse Progenitor is a Normal enemy with 134–136 (Ascension 138–141) HP. Its moves and attack pattern are listed below.

Where does Louse Progenitor appear?

It appears in: Act 2 - Hive.

More Slay the Spire 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.