Know the roster
Hoxxes IV hosts 80 documented creatures. You do not need all of them memorised, but you do need the ones that end missions.
The creature database describes every one. Sample: Barrage Infector, BET-C, Bha Barnacle, Boss, Carnivorous Larva.
Ranged before melee
Melee bugs are a damage check. Ranged bugs are a positioning check, and positioning failures are what wipe teams.
Heavies change the plan
A heavy arrival means stop what you are doing and focus it. Teams that ignore heavies lose the room.