Terrain is the difficulty
Deep Rock Galactic biomes change the cave more than the enemy list. Floor hazards, ceiling drops and sightlines all shift what a class can do.
Read the room on entry
Look up, look down, then move. Most biome deaths are environmental, not combat deaths.
Adjust the class plan
A biome that favours your class is a biome you should push. One that does not is a biome where you stay with the team.