Most Noita runs end the same way: a chain the player started and did not leave.
Mistake 1 — firing through a reaction
You spark oil, then keep shooting. The fire spreads to you. Pause and step off the moment something reacts. The enemy is not the threat; the chain is.
Mistake 2 — stacking spells blindly
Every spell adds delay and mana. A wand full of found spells locks up after one shot. Build it to chain, not to hold everything.
Mistake 3 — taking unknown perks
A purple perk you cannot read is a gamble. Some trade a flask or a wand slot for damage you may not want. Check the perk database first.
Mistake 4 — hoarding flasks
A flask saved for later does nothing if you die now. Use it below half with the threat live. Healing buys the next biome.
The two checks
Before any room: name your escape. Before any hard fight: count your flasks. Both take a second and fix most runs.
Don’t drink blind
A common mistake is quaffing an unknown potion or teleporting into a wall. Throw a potion to identify it safely before drinking, and never blink into terrain you cannot see through. Most deaths are self-inflicted reactions, not enemy damage.