Survival in Noita is reading, not reflexes. The room tells you how it kills you if you look.
Why runs end
Almost every death is a chain you began. Fire meets oil. Electricity meets water. A spell you fired bounces back. The enemy just closed it.
Read it early
When something glows, wet, or sparks, stop firing and step off. A one-second pause ends most chains before they reach you. Players who keep shooting are the ones who die.
The escape
Retreat along the wall you entered from. The middle of a room is where every threat meets. The entrance is the line you already crossed safely once.
Flasks
Use a flask the moment you drop below half and the threat is live. A flask kept for later does nothing if you die now. Healing is what buys the next biome.
The common mistakes page lists the errors that end runs fastest, and the two checks that fix most of them.
Put out the fire first
Burn damage stacks and ends runs if ignored; carry water or ice to douse yourself, and the “Bless” perk removes the panic. Keep flasks for real healing rather than sipping at trivial scratches, because a flask wasted early is a death later.