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How to Use Delirium in PoE2

Updated 21 Oct 2026 Source Path of Exile 2 in-game mechanics and community documentation, retrieved 21 October 2026 By

Delirium fills the map with fog and powerful enemies for big rewards. Surviving the fog is the challenge.

Why this matters

Delirium drops excellent loot but the fog makes enemies much deadlier, so survival matters.

Step-by-step

  1. Engage delirium when your build can survive it.
  2. Kill enemies inside the fog to keep the reward meter up.
  3. Move through the fog rather than standing still.
  4. Collect the rewards that drop as the meter fills.
  5. Retreat if the fog overwhelms you.
  6. Use delirium mirrors or orbs to add it to maps.

Key tips

  • Engage only if you can survive
  • Keep killing inside the fog
  • Move, do not stand still
  • Retreat if overwhelmed

Common mistakes

  • Standing still in the fog
  • Engaging delirium too early
  • Ignoring your defenses

Practical notes

Delirium adds a mirror that spreads fog and spawns waves, so stay near the mirror to keep rewards flowing. The longer you survive, the better the loot, so build for sustain.

Use delirium orbs on maps you can clear under pressure. Prioritize the cluster rewards over every monster. A delirium run is a balance of greed and survival, because leaving early loses loot.

Build for sustain and stay near the mirror, prioritizing cluster rewards over every monster, because leaving early loses the loot.

Build for sustain and stay near the mirror, prioritizing cluster rewards over every monster, because leaving early forfeits most of the loot.

Run it inside juiced maps from the endgame guide for the best reward density.

Delirium splinters combine into Distilled Emotions, which are spent on the Simulacrum-style encounter, so bank them instead of vendoring by accident.

Frequently asked questions

How do I survive delirium?

Keep moving, kill inside the fog to build rewards, and retreat if it overwhelms you.

More Path of Exile 2 guides

Sources

Figures and item data on this site are read from the game’s own reference wiki before publishing. Where a value could not be confirmed there, the page says so instead of filling the gap.