Companions are a once-per-run tool
A companion charges during the escape and fires a single strong effect. You get one meaningful use, so place it with care.
They are not a rotation or a cooldown you spam. Think of the companion as a planned emergency, not a habit.
Best picks for a first run
A damage companion covers the most mistakes. One big hit can end a bad room or finish a boss phase.
Avoid support companions until you know the rooms. Their value is subtle and wastes on a player still learning the map.
When to fire it
Save the companion for a boss or a room you are losing. A wasted companion on a trivial fight is gone for good.
Hold it through the early biomes. The escape the first biome page shows where pressure first spikes.
Next: Common Hades mistakes.